Stress granule–mediated ZBP1 activation drives necroptotic cell dying in non-obstructive azoospermia and testicular rising older

Court docket cases of the Nationwide Academy of Sciences, Quantity 122, Topic 33, August 2025.
SignificanceThe causes of male infertility and reproductive rising older remain largely elusive. This gaze identifies a necroptotic pathway, initiated by stress granule formation and mediated by ZBP1 and RIPK3, as a key mechanism driving the loss of testicular …
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