Proteostasis landscapes of cystic fibrosis variants repeat drug response vulnerability

Lawsuits of the National Academy of Sciences, Quantity 122, Distress 17, April 2025.
SignificanceCystic fibrosis (CF) is a lethal genetic illness with variants main to misfolding of an anion channel protein. Enhancing productive channel folding the expend of a original class of tiny molecules referred to as correctors has emerged as the contemporary CF …
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